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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD6
All Species:
13.94
Human Site:
S472
Identified Species:
38.33
UniProt:
Q96NE9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96NE9
NP_001035946.1
622
72044
S472
L
E
Q
M
N
E
E
S
L
E
V
S
P
D
M
Chimpanzee
Pan troglodytes
XP_001157624
622
72025
S472
L
E
Q
M
N
E
E
S
L
E
V
S
P
D
M
Rhesus Macaque
Macaca mulatta
XP_001083521
547
62009
S402
T
S
G
I
E
A
D
S
W
L
R
E
S
R
E
Dog
Lupus familis
XP_547810
622
71864
S472
L
E
Q
M
N
E
E
S
L
E
V
S
P
D
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0V9
622
71633
S472
L
E
P
M
P
E
E
S
L
E
V
S
P
E
M
Rat
Rattus norvegicus
Q8VII0
327
38829
K182
F
P
A
W
V
V
S
K
R
G
K
D
Y
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514866
622
71616
A472
L
E
Q
L
N
E
E
A
L
D
V
S
P
D
M
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664244
616
70369
D453
K
S
C
E
D
L
D
D
L
E
L
S
Q
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797238
705
78551
R496
H
H
Q
L
I
D
T
R
K
I
R
A
E
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
35.2
98.5
N.A.
93.5
48.5
N.A.
94
N.A.
N.A.
72.3
N.A.
N.A.
N.A.
N.A.
25.5
Protein Similarity:
100
100
50.9
99.5
N.A.
96.6
51.2
N.A.
96.6
N.A.
N.A.
83.4
N.A.
N.A.
N.A.
N.A.
44.1
P-Site Identity:
100
100
6.6
100
N.A.
80
0
N.A.
80
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
100
N.A.
86.6
6.6
N.A.
100
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
12
0
12
0
0
0
12
0
0
12
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
12
23
12
0
12
0
12
0
45
0
% D
% Glu:
0
56
0
12
12
56
56
0
0
56
0
12
12
23
12
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
0
0
0
0
12
0
0
0
0
0
% G
% His:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
12
0
0
0
0
12
0
0
0
23
0
% I
% Lys:
12
0
0
0
0
0
0
12
12
0
12
0
0
0
0
% K
% Leu:
56
0
0
23
0
12
0
0
67
12
12
0
0
0
23
% L
% Met:
0
0
0
45
0
0
0
0
0
0
0
0
0
0
56
% M
% Asn:
0
0
0
0
45
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
12
0
12
0
0
0
0
0
0
0
56
0
0
% P
% Gln:
0
0
56
0
0
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
12
12
0
23
0
0
12
0
% R
% Ser:
0
23
0
0
0
0
12
56
0
0
0
67
12
0
0
% S
% Thr:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
12
12
0
0
0
0
56
0
0
0
0
% V
% Trp:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _